Methylation is a normal biological process that occurs in healthy human bodies every minute of every day. Methylation is an important step in the conversion of homocysteine, a damaging amino acid, into the biologically safe and beneficial amino acid, methionine. In addition, methylation is required for DNA repair, as well as for the production of SAMe, which helps maintain healthy joint tissue. Methylation can be inhibited by poor or inadequate diet and unhealthy lifestyle practices. TMG (Trimethylglycine) has been shown to be a safe and effective methyl donor for the facilitation of methylation processes. TMG supplementation has been shown in clinical and non-clinical studies to support a healthy homocysteine level, which in turn supports healthy cardiovascular function.

Articles: http://www.umm.edu/altmed/articles/betaine-000287.htm