Supplementing with SAMe The manufacturing process of SAMe yields two forms, the S, S and the R, S isomers. THE S, S isomer is the active form that mediates biochemical activity in the human body, whereas the R, S form is considered to be biologically inactive. The Italian SAMe used in Double-Strength SAMe 400 is processed to yield the highest available percentage of the active pure S, S form on the market.

SAMe and Joint Function SAMe may enhance cartilage protection and promote the synthesis of proteoglycans, essential components of connective tissue. Clinical studies show an ability of SAMe to enhance mobility and movement, and promote joint comfort.*

SAMe and Neural Health SAMe-catalyzed methylation reactions promote the synthesis of neurotransmitters, which have the potential to promote enhanced mood. SAMe may also upregulate the production of phosphatidylcholine, supporting cognitive function.*

SAMe and Liver Function SAMe enhances liver synthesis of glutathione, an antioxidant. Glutathione promotes detoxification and liver protection. Studies show SAMe may protect liver tissue from injury caused by a number of toxins.*

• Dietary Supplement
• 400 mg Active S-Adenosyl Methionine Per Tablet
• Pharmaceutical Grade Made in Italy
• Enhances Mood & Neural Function
• Promotes Joint Comfort & Mobility
• Supports Liver Health & Detoxification
• Sealed in Blister Packs for Freshness & Convenience
• Suitable for Vegetarians